Kan- Piper methysticum (Kava-kava, Wati)

Didik Gunawan, suber dari Phytochemical and Ethnobotanical dB & ref-P
Kandungan Kimia dan Khasiat dari : Piper methysticum L. (Piperaceae) – Kava-kava, Wati.

Kimiawi dan Khasiat.

---

11,12-DIMETHOXYDIHYDROKAWAIN Plant:
No activity reported.
11-HYDROXY-12-METHOXYDIHYDROKAWAIN Plant:
No activity reported.
11-METHOXYNORYANGONIN Plant:
No activity reported.
11-METHOXYYANGONIN Plant:
No activity reported.
2′,4′-DIMETHYLCHALCONARINGENIN Plant:
No activity reported.
3,4-(METHYLENE-DIOXY)CINNAMYLIDENACETOL Plant:
No activity reported.
5,6,7,8-TETRAHYDROYANGONIN Plant:
No activity reported.
5-DIHYDROYANGONIN Plant:
No activity reported.
BENZOIC-ACID Plant:
Allergenic; Anesthetic; Antibacterial 33-1,250 ppm MBC=800 ug/ml; Antiotitic; Antipyretic; Antisalmonella MIC=800 ug/ml; Antiseptic 800 ug/ml; Antiyeast MFC=1,600 ug/ml; Choleretic; Expectorant; FLavor FEMA 250; Fungicide MFC=1,600 ug/ml; Insectifuge; Pesticide; Phytoalexin; Tyrosinase-Inhibitor ID50=640 uM ID50=710 uM; Uricosuric; Vulnerary
CINNAMIC-ACID Plant:
Aldose-Reductase-Inhibitor 4 ug/ml (weak activity); Allergenic; Anesthetic; Antibacterial; Antiinflammatory; Antimutagenic; Antispasmodic; Cancer-Preventive; Choleretic; Dermatitigenic; FLavor FEMA 4-40; Fungicide; Herbicide; Laxative; Lipoxygenase-Inhibitor; Pesticide; Tyrosinase-InhibitorID50=700 uM; Vermifuge
CINNAMYLIDENACETOL Plant:
No activity reported.
DEMETHOXYYANGONIN Plant:
No activity reported.
DESMETHOXYYANGONIN Plant:
No activity reported.
DIHYDROKAWAIN Plant:
Analgesic 150 mg/kg ipr mus; Anesthetic 0.25%; Anticonvulsant; Antidote (Strychnine); Antiinflammatory; Antinociceptive; Antipyretic; Antispasmodic; Endoanesthetic 5-20 mg/kg; Fungistat; MAO-B-Inhibitor; Myorelaxant 90 mg/kg; Neuroprotective; Sedative
DIHYDROKAWAIN-5-OL Plant:
No activity reported.
DIHYDROMETHYSTICIN Plant:
Analgesic; Anesthetic 0.25%; Anticonvulsant ED50 140 mg/kg orl mus; Antidote (Strychnine); Antiepileptic 800 mg/man; Antiinflammatory; Antiischemic 10-30 mg/kg ivn mus; Antinociceptive; Antipyretic; Antispasmodic; CNS-Depressant; Dermatitigenic; Endoanesthetic 5-20 mg/kg; MAO-B-Inhibitor; Myorelaxant 60 mg/kg IC50 20 mg/kg ivn mus; Neuroprotective 10-30 mg/kg ivn mus; Sedative 60 mg/kg ipr
FLAVOKAWAIN-C Plant:
No activity reported.
FLAVOKAWIN-A Plant:
No activity reported.
FLAVOKAWIN-B Plant:
No activity reported.
KAWAIN Plant:
Analgesic 300 mg/kg ipr mus; Anesthetic =cocaine 0.25%; Antiaggregant IC50=71-115 uM/l; Antiarachidonate; Anticonvulsant; Antidote (Strychnine) (3 mg/kg) IC50=98 mg/kg; Antiedemic; Antifibrillary 20 mg/kg; Antiinflammatory; Antimycotic; Antinociceptive; Antiprostaglandin; Antipyretic; Antiseptic; Antispasmodic; Antithrombotic; Antithromboxane IC50=71-115 uM/l; Anxiolytic; CNS-Depressant; Cyclooxygenase-Inhibitor; Endoanesthetic 5-20 mg/kg; Fungicide; MAO-B-Inhibitor; Myorelaxant 60 mg/kg ipr IC50 20 mg/kg ivn mus; Neurotoxic; Pesticide; Sedative 60 mg/kg ipr; Tranquilizer
KAWAINIC-ACID Plant:
No activity reported.
METHYSTICIN Plant:
Analgesic 360 mg/kg ipr mus; Anesthetic 0.25%; Anticonvulsant; Antidote (Strychnine) (Strychnine 3 mg/kg) IC=31 mg/kg; Antifibrillary 20 mg/kg; Antiinflammatory; Antiischemic 10-30 mg/kg ivn mus; Antinociceptive; Antipyretic; Antispasmodic; CNS-Depressant; Endoanesthetic 5-20 mg/kg; MAO-B-Inhibitor; Myorelaxant 45 mg/kg; Neuroprotective 10-30 mg/kg ivn mus; Neurotoxic; Psychoactive; Sedative 45 mg/kg ipr
PIPERMETHYSTINE Plant:
No activity reported.
YANGONIN Plant:
Amebicide; Anesthetic; Antibacterial; Antiinflammatory; Antipyretic; Antispasmodic; CNS-Depressant; MAO-B-Inhibitor; Myorelaxant 45 mg/kg iprIC50 5 mg/kg ivn mus; Pesticide; Sedative 45 mg/kg ipr

---

ppm = parts per million
tr = trace